Recommended literature

• Cooper A & Dryden DT (1984) Allostery without conformational change. A plausible model. European Biophysics Journal 11(2):103-109.
  This paper lays the theoretical foundation for the model of entropy-driven allostery. (Download)

• Wand AJ, Moorman VR, & Harpole KW (2013) A surprising role for conformational entropy in protein function. Topics in Current Chemistry 337:69-94.
  Discusses the significance of conformational entropy in protein function. (Download)

• Kornev AP, Haste NM, Taylor SS, & Ten Eyck LF (2006) Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism. Proceedings of the National Academy of Sciences of the USA 103(47):17783-17788.
  Presents the first detailed description of the LSP-alignment and its application in identifying conserved spatial patterns in protein kinases. (Download)

• Popovych N, Sun S, Ebright RH, & Kalodimos CG (2006) Dynamically driven protein allostery. Nature Structural & Molecular Biology 13(9):831-838.
  Provides the first experimental confirmation of entropy driven allostery as observed in the Catabolite Activator Protein. (Download)

• Kornev AP (2018) Self-organization, entropy and allostery. Biochemical Society Transactions 46(3):587-597.
  Integrates concepts of entropy-driven allostery with self-organization of coupled oscillators. (Download)

• Kornev AP, Aoto PC, & Taylor SS (2022) Calculation of centralities in protein kinase A. Proceedings of the National Academy of Sciences of the USA 119(47):e2215420119.
  Introduces the initial application of LSP-alignment to analyze Molecular Dynamics. (Download)

• Kornev AP, Weng JH, Maillard RA, & Taylor SS (2024) Gauging Dynamics-driven Allostery Using a New Computational Tool: A CAP Case Study. Journal of Molecular Biology 436(2):168395.
  Demonstrates the ability of PRNs based on LSP-alignment to assess protein entropy related to thermal motions. (Download).